Prostate MRI: Evaluating Tumor Volume and Apparent Diffusion Coefficient as Surrogate Biomarkers for Predicting Tumor Gleason Score
نویسندگان
چکیده
منابع مشابه
Prostate MRI: evaluating tumor volume and apparent diffusion coefficient as surrogate biomarkers for predicting tumor Gleason score.
PURPOSE To investigate whether tumor volume derived from apparent diffusion coefficient (ADC) maps (VolumeADC) and tumor mean ADC value (ADCmean) are independent predictors of prostate tumor Gleason score (GS). EXPERIMENTAL DESIGN Tumor volume and GS were recorded from whole-mount histopathology for 131 men (median age, 60 years) who underwent endorectal diffusion-weighted MRI for local stagi...
متن کاملPersonalized Medicine and Imaging Prostate MRI: Evaluating Tumor Volume and Apparent Diffusion Coefficient as Surrogate Biomarkers for Predicting Tumor Gleason Score
Purpose: To investigate whether tumor volume derived from apparent diffusion coefficient (ADC)maps (VolumeADC) and tumormeanADCvalue (ADCmean) are independent predictors of prostate tumorGleason score (GS). Experimental Design: Tumor volume andGSwere recorded fromwhole-mount histopathology for 131 men (median age, 60 years) who underwent endorectal diffusion-weightedMRI for local staging of pro...
متن کاملProstate MRI: Evaluating tumor volume and apparent diffusion coefficient as surrogate biomarkers for predicting tumor Gleason score Running Title: Diffusion-weighted MRI in prostate cancer: prediction of aggressiveness Original Research
Purpose To investigate whether tumor volume derived from apparent diffusion coefficient (ADC) maps (VolumeADC) and tumor mean ADC value (ADCmean) are independent predictors of prostate tumor Gleason score (GS). Materials and Methods Tumor volume and GS were recorded from whole-mount histopathology for 131 men (median age, 60) who underwent endorectal diffusion-weighted magnetic resonance imagin...
متن کاملPredicting Gleason Scores of Prostate Cancer Using Combined Trace Apparent Diffusion Coefficient and Tumor Volume
Introduction With increasing life expectancy, prostate cancer (PCA) is becoming one of the most common forms of malignancy in men. Clinically, the Gleason Scores (GS) are commonly used to assess the aggressiveness of PCA with grades from 1 to 5. The GS is one of the parameters in a strategy of staging system that predicts prognosis and helps decision of treatment options. Magnetic resonance (MR...
متن کاملDiffusion-weighted MRI of peripheral zone prostate cancer: comparison of tumor apparent diffusion coefficient with Gleason score and percentage of tumor on core biopsy.
OBJECTIVE The objective of our study was to determine the relationship between the apparent diffusion coefficient (ADC) value on diffusion-weighted imaging (DWI) and Gleason score of prostate cancer and percentage of tumor involvement on prostate core biopsy. MATERIALS AND METHODS We performed a retrospective study of 57 patients with biopsy-proven prostate cancer who underwent endorectal MRI...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2014
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-14-0044